[HTML][HTML] A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

D Li, X Chang, JJ Connolly, L Tian, Y Liu, EJ Bhoj… - Scientific reports, 2017 - nature.com
… We conducted a genome-wide association study (GWAS) of anorexia nervosa (AN) using
a … of a specific genetic risk factor that approached genome-wide significance (rs929626 in …

A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

V Boraska, CS Franklin, JAB Floyd, LM Thornton… - Molecular …, 2014 - cdr.lib.unc.edu
Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by … Neither
candidate gene studies nor an initial genome wide association study (GWAS) have yielded …

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

…, Anorexia Nervosa Genetics Initiative… - Nature …, 2019 - nature.com
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric
origins for anorexia nervosa | … Genome-wide association study identifies eight risk loci and …

[HTML][HTML] Genome-wide association study reveals first locus for anorexia nervosa and metabolic correlations

L Duncan, Z Yilmaz, R Walters, J Goldstein… - The American journal …, 2017 - ncbi.nlm.nih.gov
… 2 of anorexia nervosa was 0.20 (SE=0.02), suggesting that a … GWAS loci for complex
disorders, the region implicated is … dysregulation of appetite and weight in anorexia nervosa. …

[HTML][HTML] Erratum: A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

D Li, X Chang, JJ Connolly, L Tian, Y Liu, EJ Bhoj… - Scientific reports, 2017 - nature.com
Erratum: A genome-wide association study of anorexia nervosa suggests a risk locus
implicated in dysregulated leptin signaling | Scientific Reports … In the author list, Hakon …

Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa

…, Eating Disorders Working Group of the … - American journal of …, 2017 - Am Psychiatric Assoc
… modest odds ratio of 1.2 and implicates a broad region encompassing … Our results, in contrast,
suggest that genetic factors may … dysregulation of appetite and weight in anorexia nervosa. …

Erratum: A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling (Scientific Reports (2017) 7 (3847

L Dong, X Chang, JJ Connolly, L Tian, Y Liu… - SCIENTIFIC …, 2017 - research.unipg.it
… We conducted a genome-wide association study (GWAS) of anorexia nervosa (AN) using
a … of a specific genetic risk factor that approached genome-wide significance (rs929626 in …

Genetics of anorexia nervosa: An overview of genome-wide association studies and emerging biological links

C de Jorge Martínez, G Rukh, MJ Williams… - Journal of Genetics and …, 2022 - Elsevier
… the study was well-powered, suggesting that they may not be involved in aetiology of AN. …
This study identified 77 genome-wide significant loci for body fat percentage (BF%) and 174 …

[HTML][HTML] Suggestive evidence for causal effect of leptin levels on Risk for anorexia nervosa: results of a mendelian randomization study

T Peters, J Antel, R Naaresh, BH Laabs… - Frontiers in …, 2021 - frontiersin.org
… of the most recent genome-wide association study (GWAS) for … Our study was stimulated by
recent case reports suggesting … not implicate a causal effect. AN itself has no causal effect on …

Genetics and neurobiology of eating disorders

CM Bulik, JRI Coleman, JA Hardaway… - Nature …, 2022 - nature.com
… the most recent genome-wide association study (GWAS) of … VTA region 112 , implicating that
a loss of leptin signaling in VTA … suggest an overlap in the biological regulation of AN, leptin, …